A Case of Diffuse Large B-Cell Lymphoma Mimicking Primary Effusion Lymphoma-Like Lymphoma

A Case of Diffuse Large B-Cell Lymphoma Mimicking Primary Effusion Lymphoma-Like Lymphoma

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A 93-year-old female was transferred to the emergency ward of our hospital due to disturbance of consciousness and hypotension.Computed tomography showed bilateral pleural and pericardial effusion without evidence of tumor masses or lymphadenopathy.Cytodiagnosis of pleural effusion revealed proliferation of atypical lymphoid-like NUTMEG cells with pan-B surface markers.We suspected primary effusion lymphoma-like lymphoma; however, the monoclonality of these cells was not confirmed.Cytodiagnosis of bone marrow revealed lymphoma cells Mixing Bowl Stands with monoclonal B-cell markers.

These findings prompted a diagnosis of diffuse large B-cell lymphoma with bone marrow invasion.In the case of pericardial or pleural effusion, clinicians should consider carefully both hematological malignancy and its classification.